Risk Factors for Long-term Opioid Use

Stanford University

Status: Completed

Conditions: Pain Syndrome

Treatments: Other: No intervention - retrospective observational cohort study

Study type: Observational

Funder types: Other

Identifiers

NCT04928131

43803

Details and patient eligibility

About

Surgeons often see patients with pain to exclude organic pathology and consider surgical treatment. We examined factors associated with long-term opioid therapy among patients with foot/ankle, anorectal, and temporomandibular joint pain to aid clinical decision making.

Using the IBM MarketScan® Research Database, we conducted a retrospective cohort analysis of patients aged 18-64 with a clinical encounter for foot/ankle, anorectal, or temporomandibular joint pain (January 2007-September 2015). Multivariable logistic regression was used to estimate adjusted odds ratios for factors associated with long-term opioid therapy, including age, sex, geographic region, pain condition, psychiatric diagnoses, and surgical procedures in the previous year.

Enrollment: 1,500,392 patients

Sex: All

Ages: 18 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 18-64 years old
• at least one encounter for anorectal, foot/ankle, or TMJ pain
• Marketscan continuous enrollment for 1 year prior and 1 year after the index pain encounter

Trial design

1,500,392 participants in 3 patient groups

Anorectal

Description:

Patients presenting with anorectal pain.

Treatment:

Other: No intervention - retrospective observational cohort study

TMJ

Description:

Patients presenting with temporomandibular joint pain.

Treatment:

Other: No intervention - retrospective observational cohort study

Foot/Ankle

Description:

Patients presenting with foot and ankle pain.

Treatment:

Other: No intervention - retrospective observational cohort study