Risk Factors for Postoperative Spinal Epidural Hematoma Following Posterior Thoracic Spinal Surgery in a Single Institute

Peking University

Status: Completed

Conditions: Spinal Epidural Hematoma; Thoracic Surgery

Study type: Observational

Funder types: Other

Identifiers

NCT04961424

M2020006

Details and patient eligibility

About

This is a retrospective, observational single-center study. The studies is to investigate the incidence of posterior epidural spinal hematoma(PSEH) and recognize the risk factors for it in a cohort of patients undergoing posterior thoracic surgery in isolation.

Full description

The study enrolled patients from January 2010 to December 2019, patients who developed PSEH after posterior thoracic surgery and underwent the hematoma evacuation. For each PSEH patients, 2 or 3 controls who did not develop the PSEH, underwent the same procedures of similar complexity at the same section of thoracic spine in the same period were collected. The preoperative and intraoperative factors, blood pressure related factors and radiographic parameters were collected to identify possible risk factors by comparing between two groups.

Enrollment: 22 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Subjects satisfying the following criteria will be considered eligible for enrollment in this study:

1. Patient is ≥ 18 years and < 80 years of age;
2. Patient who received thoracic decompression surgery via posterior approach
3. Patient who diagnosed as symptomatic spinal epidural haematoma and received revision surgery.

Exclusion criteria

1. Thoracic spinal stenosis caused by trauma, tumor, infectious, deformity and other disease;
2. Symptomatic spinal epidural haematoma happened at cervicothoracic and thoracolumbar junction;
3. Initial surgeries were performed at other hospital;
4. Incomplete clinical data.

Trial design

22 participants in 2 patient groups

Symptomatic spinal epidural hematoma Group

Description:

Patients who performed thoracic decompression surgery and developed neurological deficit after surgery due to the symptomatic spinal epidural hematoma were enrolled into case group.

Control group

Description:

hose who did not develop the symptomatic spinal epidural hematoma, underwent the same procedures of similar complexity at the same section of thoracic spine in the same period (the same year or the following year) were randomly selected from the pool of patients.