Risk Factors of Anxiety and Depression in Patients With Herpes Zoster Neuralgia

Huazhong University of Science and Technology

Status: Enrolling

Conditions: Herpes Zoster

Treatments: Diagnostic Test: Hospital Anxiety and Depression Scale

Study type: Observational

Funder types: Other

Identifiers

NCT06449547

TJ-IRB202401075

Details and patient eligibility

About

The goal of this observational study is to explore risk factors of anxiety and depression in patients with herpes zoster neuralgia, and the changes of certain serum biomarkers and functional brain magnetic resonance images of these patients.

Full description

Patients with herpes zoster neuralgia will be recruited and take Hospital anxiety depression rating scale (Hospital anxiety and 'scale, HADS) evaluation. According to the HADS Scores, patients will be divided into depression group and no depression, or anxiety group and no anxiety group. The clinical data the of two groups will be collected and statistically analyzed to explore the risk factors of anxiety and depression, including the changes of serum biomarkers and functional brain magnetic resonance imaging in patients with herpes zoster neuralgia accompanying anxiety or depression.

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age more than 18 years old
2. Diagnosed as herpes zoster neuralgia
3. Signing informed consent

Exclusion criteria

1. Unable to complete the scale assessment
2. History of mental illness

Trial design

600 participants in 4 patient groups

patients with anxiety

Description:

Patients in this group suffered from herpes zoster neuralgia and had a score more than or equal to 8 for Hospital Anxiety and Depression Scale- Anxiety questionnaire.

Treatment:

Diagnostic Test: Hospital Anxiety and Depression Scale

patients without anxiety

Description:

Patients in this group suffered from herpes zoster neuralgia and had a score less than 8 for Hospital Anxiety and Depression Scale- Anxiety questionnaire.

Treatment:

Diagnostic Test: Hospital Anxiety and Depression Scale

patients with depression

Description:

Patients in this group suffered from herpes zoster neuralgia and had a score more than or equal to 8 for Hospital Anxiety and Depression Scale- Depression questionnaire.

Treatment:

Diagnostic Test: Hospital Anxiety and Depression Scale

patients without depression

Description:

Patients in this group suffered from herpes zoster neuralgia and had a score less than 8 for Hospital Anxiety and Depression Scale- Depression questionnaire.

Treatment:

Diagnostic Test: Hospital Anxiety and Depression Scale