Risk Factors of ICU-acquired Weakness (ICU-AW)

Zhejiang University

Status: Unknown

Conditions: ICU Acquired Weakness

Study type: Observational

Funder types: Other

Identifiers

NCT04932330

2021-0041

Details and patient eligibility

About

We conducted a retrospective study of critical ill patients who used ECMO during their ICU stay. ICU-AW was diagnosed at the time when patients discharged and had a Medical Research Council (MRC) sum score < 48 out of a maximal score of 60. We divided patients to ICU-acquired weakness group and no ICU-acquired weakness group and compared their clinical characteristics. Baseline characteristics and therapy details were collected from the case report forms and inspection reports. Univariable analysis and logistic regression analysis were used to analyze clinical characteristics of individuals and to find risk factors of ICU-AW.

Enrollment: 85 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Critical ill patients who used extracorporeal membrane oxygenation during their ICU stay. Patients were recruited from the general ICU of the second affiliated hospital of Zhejiang University, between March 2017 to March 2020.

Exclusion criteria

• Patients who was less than 18 years old, had been proven or suspected neurological impairment, using extracorporeal membrane oxygenation less than 24 hours, severe head or spinal cord injury and pregnant woman.

Trial design

85 participants in 2 patient groups

ICU-acquired weakness group

Description:

Patients receiving extracorporeal membrane oxygenation support who had a Medical Research Council (MRC) sum score \< 48 out of a maximal score of 60 when discharged.

no ICU-acquired weakness group

Description:

Patients receiving extracorporeal membrane oxygenation support who had a Medical Research Council (MRC) sum score ≥ 48 out of a maximal score of 60 when discharged.