Risk Factors of Preterm Birth Born in Hospital：a Prospective Multicenter Case-control Study (RFPTB)

Fudan University

Status: Completed

Conditions: Risk Factors

Study type: Observational

Funder types: Other

Identifiers

NCT03602625

EKYYRFPTBMC

Details and patient eligibility

About

The purpose of this study is to explore the perinatal risk factors of preterm birth in China.

Full description

Preterm birth is a global scourge, and the leading cause of newborn deaths (babies in the first 4 weeks of life) and raised to the leading cause of death among children under 5 years of age, responsible for approximately 1 million deaths in 2015. In China, the prevalence of preterm increased from 4~5% in 1990s to 7~10% in 2010. Preterm birth become a burden to both the family and society. Therefore, the risk factors of preterm birth become the critical issue of both Obstetrics and Neonatology. More importantly, few multicenter prospective studies on risk factors of preterm birth included potential reasons such as maternal occupation, psychology condition and lifestyles during pregnancy were conducted in China. Thus, the aim of our study is to explore the perinatal risk factors of preterm birth nowadays in China.

Enrollment: 6,000 patients

Sex: All

Ages: Under 28 days old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Live-born infants >20weeks of gestational age

Exclusion criteria

• Stillbirth

Trial design

6,000 participants in 2 patient groups

Preterm group

Description:

All the live-born infants with gestational age less than 37weeks and more than 20weeks born in the cooperative hospital every day or every two or three days.

Term group

Description:

The one next-live-born infants with gestational age at 37weeks or more than 37weeks.