Risk Factors Related to Postoperative Acute Kidney Injury in Elderly Patients Undergoing Joint Replacement

Xuzhou Medical University

Status: Unknown

Conditions: Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT04132921

XYFY2020-KL050-01

Details and patient eligibility

About

Total hip arthroplasty refers to the replacement of the femoral head and acetabulum damaged by disease or trauma with an artificial hip joint, thereby restoring joint activity and original function. Acute kidney injury is a common complication after total hip arthroplasty. Previous studies have shown that the incidence of acute kidney injury after hip replacement is as high as 21.9%. Acute kidney injury has become a global safety issue, and the occurrence of acute kidney injury can lead to an increase in hospital stay, medical costs and increased risk of death.There is currently no global survey of the incidence of AKI, and only a number of studies have been conducted on specific patient groups (eg, inpatients, intensive care units [ICU] patients or children) due to differences in study design and definition of acute kidney injury.

Full description

The incidence and prevalence of different studies vary widely, ranging from 0.32% to 44.30%. There are few studies on the risk factors associated with acute kidney injury after total hip arthroplasty, and early acute kidney injury is often overlooked due to the limitations of the current KDIGO-based diagnostic method. Therefore, it is particularly important for clinicians to understand the risk factors for postoperative acute kidney injury .

Enrollment: 1,500 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients age 65 or older
• One-sided joint replacement;
• ASA score grade I-III

Exclusion criteria

• Emergency surgery patients;
• Patients with severe liver and kidney dysfunction;
• Missing related data;
• Serious systemic diseases before surgery;

Trial design

1,500 participants in 2 patient groups

Patients with AKI

Description:

Patients with AKI after joint replacement

Patients without AKI

Description:

Patients without AKI after joint replacement