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Risk Indicators in Patients With Ventricular Fibrillation During Acute Myocardial Infarction

H

Heidelberg University

Status

Unknown

Conditions

Sudden Cardiac Death
Acute Myocardial Infarction

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Sudden cardiac death is in most cases triggered by ischemia-related ventricular tachyarrhythmias and accounts for 50% of deaths from cardiovascular disease in developed countries. Chronic elevation of indicators of coagulation activation has been found in patients with coronary heart disease , but a role of coagulation activation and proinflammatory state as a potential risk factor for ventricular fibrillation (VF) during acute myocardial infarction has not been investigated.

Full description

Sudden cardiac death (SCD) is in most cases triggered by ischemia-related ventricular arrhythmias and is responsible for 50% of the mortality from cardiovascular disease in developed countries (1). Chronic elevation of indicators of coagulation activation and inflammation has been found in patients with coronary heart disease and may contribute to vasculatory disorders probably contributing to the development of arrhythmogenesis. However, the role of coagulation activation as a potential risk factor for ventricular fibrillation during acute myocardial infarction has not been investigated yet.

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

ST-elevation myocardial infarction ventricular fibrillation during acute MI

Exclusion criteria

NSTEMI coagulation disorders, e.g.intake of coumadin

Trial contacts and locations

1

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Central trial contact

Martina Brückmann, MD, Dr.; Elif Elmas, MD, Dr.

Data sourced from clinicaltrials.gov

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