Risk of Dry Eye Post Different Surgeries for Blepharoptosis Repair

Clalit Health Services

Status: Unknown

Conditions: Blepharoptosis

Treatments: Procedure: Müller's muscle-conjunctival resection procedure; Procedure: White line advancement; Procedure: Levator advancement

Study type: Interventional

Funder types: Other

Identifiers

NCT02501187

Ptosis-01

Details and patient eligibility

About

Blepharoptosis, inferodisplacement of the upper eyelid, can be congenital or acquired. Acquired Blepharoptosis is usually aponeurotic, due to stretching or disinsertion of the levator aponeurosis. Treatment is surgical and can be performed by three common procedures - Levator advancement, Müller's muscle-conjunctival resection procedure and White line advancement. A number of reports inspected the possibility that Blepharoptosis repair procedures may cause deterioration in dry eye status. The investigators would like to assess whether there is a difference between the different procedures in their influence on dry eye status.

Enrollment: 75 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ptosis which indicate surgical repair
• The ptosis must be suitable for repair in any of the procedures

Exclusion criteria

• Systemic disease which may cause ocular surface disease (eg Sjogren disease)
• Previous orbital or eyelid surgery
• Significantly dry eyes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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75 participants in 3 patient groups

Patients operated for ptosis by levator advancement

Experimental group

Description:

patients undergoing surgical repair for aponeurotic ptosis by the procedure- levator advancement.

Treatment:

Procedure: Levator advancement

Patients operated for ptosis by white line advancement

Experimental group

Description:

patients undergoing surgical repair for aponeurotic ptosis by the procedure- white line advancement

Treatment:

Procedure: White line advancement

Patients operated for ptosis by Müller resection

Experimental group

Description:

patients undergoing surgical repair for aponeurotic ptosis by the procedure- Müller's muscle-conjunctival resection.

Treatment:

Procedure: Müller's muscle-conjunctival resection procedure