Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study

University of Khartoum

Status: Completed

Conditions: Incidence of Thyroid Cancer in Long Standing MNG

Treatments: Diagnostic Test: Histopathology

Study type: Observational

Funder types: Other

Identifiers

NCT06405919

UofK

Details and patient eligibility

About

To determine the incidence of thyroid cancer in patients with long standing goitres presenting for surgery.

Full description

This is a prospective cohort study The objective is to determine the incidence of cancer in patients with long standing goitres( more than 10 years ) who present for surgery in Khartoum Teaching Hopspital - Sudan.

Introduction: goitre is endemic in Sudan with prevalence ranging between 5-42% in different regions of the country. Patients are referred for surgery only if they develop pressure symptoms.

The incidence of thyroid carcinoma is high in endemic goitrous areas. Determining the risk of cancer in patient with long standing goitres may help in early early referral and early surgical intervention.

Methods: This is prospective cohort study including 160 patients with long standing goitrers of 10 years or more who presented from March 2017 to September 2017 to Khartoum Teaching Hospital-Sudan

Enrollment: 160 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients with long standing goitres of 10 years or more

Exclusion criteria

• Non

Trial design

160 participants in 1 patient group

Patients with goitres 10 years or more

Description:

Patients with long standing multinodular goitres of 10years or more presenting to surgical unit in Khartoum Teaching Hospital -Sudan. Checking incidence of malignancy in this group.

Treatment:

Diagnostic Test: Histopathology