Risk of Venous Thromboembolism in Critically Ill Patients With Severe COVID-19

Vall d'Hebron University Hospital (HUVH)

Status

Completed

Conditions

Venous Thromboses, Deep

Sars-CoV2

COVID-19

Pulmonary Embolism

Venous Thromboembolism

Venous Thrombosis Pulmonary

Critical Illness

SARS-CoV Infection

Venous Thromboses

Pulmonary Embolism and Thrombosis

Treatments

Diagnostic Test: Duplex ultrasound and Computed Tomography Angiography

Study type

Observational

Funder types

Other

Identifiers

NCT04374617

PR(AG)213/2020

Details and patient eligibility

About

Severe COVID-19 patients at a high risk of venous thromboembolism. We studied patients in 2 intensive care units of university hospitals in Barcelona and Badalona, Spain. We performed a cut-off screening of deep venous thrombosis (DVT) with bilateral duplex ultrasound to 230 patients.

Full description

SARS-CoV-2 infection has been associated with coagulation disorders and increased risk of venous thromboembolism (VTE). The aim of the study is to determine the cumulative incidence of VTE in critically ill patients with COVID-19 and its impact on prognosis.

Methods Cohort study of critically ill patients due to COVID-19. A bilateral venous compression (CUS) ultrasound screening of the lower extremities was performed during a cut-off period in 2 intensive care units of university hospitals in Spain. Asymptomatic and symptomatic VTE were registered: pulmonary embolism (PE) (diagnosed by CT-angiography) and deep venous thrombosis (DVT). The characteristics of the patients, results of their blood tests and their evolution after 7 days of follow-up were recorded.

Enrollment

230 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria