Risk Stratification, Early Prevention and Treatment Strategies for Arrhythmogenic Cardiomyopathy (STARTER)

Xi'an Jiaotong University

Status: Enrolling

Conditions: Arrhythmogenic Cardiomyopathy

Treatments: Other: Diagnosis of ACM

Study type: Observational

Funder types: Other

Identifiers

NCT06352307

XJTU1AF2023LSK-532

Details and patient eligibility

About

This study will include patients diagnosed with Arrhythmogenic cardiomyopathy (ACM) in the First Affiliated Hospital of Xi 'an Jiaotong University and other centers, and collect clinical data and biological samples of patients with different ACM phenotypes. Through the establishment of disease cohort and long-term follow-up, to explore the disease characteristics, development law, clinical characteristics, natural course of disease and long-term prognosis of ACM.

Full description

This study will include patients diagnosed with Arrhythmogenic cardiomyopathy (ACM) in the First Affiliated Hospital of Xi 'an Jiaotong University and other centers, and collect clinical data and biological samples of patients with different ACM phenotypes. Through the establishment of disease cohort and long-term follow-up, to explore the disease characteristics, development law, clinical characteristics, natural course of disease and long-term prognosis of ACM.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >18 years old.
• The diagnosis of ACM was confirmed by cardiac ultrasound, electrocardiogram, magnetic resonance angiography, pathological examination and gene sequencing.
• Patients or their families agreed to participate in the study and authorized informed consent.

Exclusion criteria

• Incomplete clinical data.
• Do not agree to the inclusion or refuse to authorize the informed consent.

Trial design

1,500 participants in 3 patient groups

Right ventricular ACM group

Description:

The patients mainly had right ventricular enlargement and right ventricular fibrous adipose tissue replacement, and were diagnosed with right ventricular ACM.

Treatment:

Other: Diagnosis of ACM

Left ventricular ACM group

Description:

The patients mainly had left ventricular enlargement and left ventricular fibroadipose tissue replacement, and were diagnosed with left ventricular ACM.

Treatment:

Other: Diagnosis of ACM

Biventricular ACM group

Description:

The patients mainly had biventricular enlargement and fibroadipose tissue replacement, and were diagnosed with biventricular ventricular ACM.

Treatment:

Other: Diagnosis of ACM