Risk Stratification for Patients With Hospital-diagnosed Advanced Lung Cancer

UNC Lineberger Comprehensive Cancer Center

Status: Completed

Conditions: Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05722847

LCCC2205

Details and patient eligibility

About

This study explores whether supportive care interventions that might reduce rehospitalization could be implemented and feasible, in subjects within a high-risk group of subjects with newly diagnosed hospitalized advanced lung cancer (ALC).

This study screened 50 subjects from health records and consented to 15 of these screened subjects. These 15 subjects responded to PRO questionnaires.

Full description

Subjects will be considered high risk if they have small cell histology, longer than 8 days hospitalization, high comorbidity, emergency department use or hospitalization in the previous 6 months, prescription of a wheelchair on hospital discharge, or Black and/or Hispanic race. Supportive care interventions such as navigation and palliative care will be recommended for this group.

All hospitalized subjects with newly diagnosed ALC will be offered web- or telephone-based patient-reported outcome (PRO) symptom monitoring for 90 days following hospital discharge if they provide consent. Medical record evaluation of consented subjects will provide data for risk assessment and the high-risk group definition. Healthcare utilization including emergency department visits, hospitalizations, outpatient palliative care, and cancer treatment received will be compared.

Enrollment: 18 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria for Patient Participants:

1. Age ≥ 18 years at the time of screening.
2. Hospital-diagnosed Advanced lung cancer with histological confirmation of disease or suspected lung cancer in the opinion of the treating oncologist.

For PROs only

1. Able to complete a web-based or telephonic symptom survey.

Exclusion Criteria for Patient Participants:

1. Enrollment in hospice upon discharge from the index hospitalization For PROs only

2. Inability to read or speak English.

3. Dementia, altered mental status, or any psychiatric condition as determined by the clinical or study team that would prohibit the understanding or rendering of informed consent.

4. Current incarceration.

5. Any condition that would prohibit the patient from completing PROs

Inclusion Criteria for Health Care Provider Participants:

1. Thoracic medical oncology physicians, advance practice providers, and nurse navigators work in the study site and respond to the survey that assesses acceptability.

Trial design

18 participants in 3 patient groups

Low risk

Description:

Subjects will be considered low risk if they have non-small cell histology, a length of hospital stay \<= 8 days, no or low comorbidity, no emergency department use or hospitalization in the 6 months prior, no wheelchair requirement when hospital discharge, or other than Black and/or Hispanic race.

High risk

Description:

Subjects will be considered high risk if they have small cell histology, a length of hospital stay \> 8 days, high comorbidity, emergency department use or hospitalization in the 6 months prior, prescription of a wheelchair when hospital discharge, or Black and/or Hispanic race.

Health Care Providers Group

Description:

Thoracic medical oncology physicians, advance practice providers, and nurse navigators respond to the survey that assess acceptability.