Risk Stratification for Venous Thromboembolism in Hospitalized Medical Patients (RISE)

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Pulmonary Embolism; Venous Thromboembolism; Hospital Acquired Condition; Embolism and Thrombosis; Deep Vein Thrombosis; Mobility Limitation; Venous Thromboses

Study type: Observational

Funder types: Other

Identifiers

NCT04439383

RISE

Details and patient eligibility

About

Hospital-acquired venous thromboembolism (HA-VTE) is one of the leading preventable causes of in-hospital mortality, but prevention of VTE in hospitalized medical patients remains challenging, as preventive measures such as pharmacological thromboprophylaxis (TPX) need to be tailored to individual thrombotic risk.

The broad objective of this project is to improve VTE prevention strategies in hospitalized medical patients by prospectively examining VTE risk factors (including mobility) and comparing existing risk assessment models.

Enrollment: 1,353 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• Admitted for hospitalization >24 hours on a general internal medicine ward
• Informed consent as documented by signature

Exclusion criteria

• Need for therapeutic anticoagulation (e.g., atrial fibrillation)
• Life expectancy <30 days
• Insufficient proficiency of the German or French language
• Unwilling to provide informed consent
• Prior enrolment in the study