Risk Stratification in End Stage Renal Disease (ESRD) - ISAR Study

Technical University of Munich

Status: Unknown

Conditions: Chronic Kidney Disease; Cardiovascular Event; End Stage Renal Disease; Sudden Cardiac Death

Study type: Observational

Funder types: Other

Identifiers

NCT01152892

ISAR ESRD 01 2010

Details and patient eligibility

About

The purpose of this study is to evaluate the use of non-invasive markers of the autonomic function and micro- and macrocirculation to predict mortality and cardiovascular end points in end-stage renal disease patients. Furthermore we aim at getting new insight into the insufficiently understood pathophysiology leading to excessively high cardiovascular and non-cardiovascular mortality in dialysis patients.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18 or older
2. End-stage renal disease (ESRD) and receiving maintenance hemodialysis

Exclusion criteria

1. Any clinically significant infection.
2. pregnancy
3. history of malignant disease with a prognostic life expectancy less than 24 months
4. missing of written and informed consent