Risk Stratifying COPD Exacerbations (ProECOPD_23)

Pamela Youde Nethersole Eastern Hospital

Status: Enrolling

Conditions: COPD Exacerbation

Treatments: Other: Observation only

Study type: Observational

Funder types: Other

Identifiers

NCT05852327

ProECOPD_23

Details and patient eligibility

About

To identify clinical characteristics on presentation which predict differential outcomes in patients with exacerbation of COPD.

Full description

Exacerbations of COPD (ECOPD) are heterogenous but are often considered as a single clinical entity. Clinical characteristics on presentation may predict outcome of patients with ECOPD.

DECAF score was previously proposed to predict in-hospital mortality but has not been validated in Asian subjects. ROME classification was recently proposed to better risk stratify ECOPD according to symptoms, physiological parameters and laboratory findings on admission, but no prospective validation study is available so far.

This study aims to identify clinical characteristics on presentation to predict outcome of patients with ECOPD.

Enrollment: 500 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Background history of COPD, defined by the GOLD 2023 guidelines
• Presented with exacerbation of COPD, defined by the GOLD 2023 guidelines
• Age >= 18 years old
• Informed consent available

Exclusion criteria

• Age < 18 years old
• No informed consent

Trial design

500 participants in 1 patient group

COPD

Description:

Subjects with COPD exacerbation

Treatment:

Other: Observation only