Risks of Bacterial and Fungal Superinfection in Patients With COVID-19

The University of Queensland

Status: Completed

Conditions: COVID-19

Treatments: Other: Previously admitted COVID-19 patients in intensive care units

Study type: Observational

Funder types: Other

Identifiers

NCT05256316

HREC/2021/QRBW/74171

Details and patient eligibility

About

Infection with bacteria or fungi can be deadly. Often, these types of infections can lead to an increase in the severity of illness requiring intensive care unit (ICU) admission, prolonged duration of treatment and further risks associated with additional infections and superinfections. These are also called hospital acquired secondary infections. Patients who contract COVID-19 and require an ICU admission are at increased risk of contracting these secondary infections, and receive certain medications that can lower your body's immune response. In COVID-19 patients who require these treatments, it is unclear what affect these medications can have on developing an additional infection as well as the rate of recovery/survival. This study is evaluating the effect these medications have on the development of secondary infections and rate of survival of COVID-19 patients that have been admitted to ICUs.

Enrollment: 790 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hospital admission date from 1 July 2020 to 30 June 2021
• Positive test for COVID-19 collected within 1 week of admission date
• ICU admission within 60 days after hospital admission date

Exclusion criteria

• Hospital admission shorter than 5 days
• Persons younger than 18 years of age

Trial design

790 participants in 1 patient group

Previously admitted COVID-19 patients in intensive care units

Description:

Infectious Diseases Physicians from participating hospitals will identify patients with COVID-19 admitted to their hospital who had an intensive care unit stay during the first 60 days after hospital admission.

Treatment:

Other: Previously admitted COVID-19 patients in intensive care units