Risperidone for the Treatment of Cocaine Dependence - 7

National Institutes of Health (NIH)

Status and phase: Completed; Phase 2

Conditions: Cocaine-Related Disorders

Treatments: Drug: Risperidone

Study type: Interventional

Funder types: NIH

Identifiers

NCT00000342

NIDA-3-0010-7

Y01-3-0010-7

Details and patient eligibility

About

The purpose of this study is to evaluate clinical safety and pharmacological efficacy in the treatment of cocaine dependence, to evaluate impact of treatment on craving, and to correlate evidence of baseline neurotoxic damage of cocaine with treatment outcome and clinical side-effects.

Sex: All

Ages: 21 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

M/F ages 21-50. Meet DSM-IV criteria for cocaine dependence. Agree to conditions of the study and sign informed consent.

Exclusion criteria

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.