Rituximab Desensitization Therapy for Patients on the Waiting List for Kidney Transplant

University of Wisconsin (UW)

Status: Withdrawn

Conditions: End Stage Renal Disease

Treatments: Drug: rituximab

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00167791

H-2004-0265

RIST

Details and patient eligibility

About

This is a study of patients who have a high risk of kidney rejection before kidney transplant. The hypothesis is that treatment with a medication called rituximab will make it possible for them to receive a kidney transplant from a donor who previously did not present a good match.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Active status on a kidney transplant waiting list with positive cross match against a living donor

Exclusion criteria

• Receipt of a live vaccine within 4 weeks prior to randomization
• Previous Treatment with Rituximab

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)