Robotic Versus Laparoscopic Liver Resection for Hepatocellular Carcinoma

Ente Ospedaliero Cantonale, Bellinzona

Status: Completed

Conditions: Hepatocellular Carcinoma

Treatments: Procedure: Minimally invasive liver resection

Study type: Observational

Funder types: Other

Identifiers

NCT06496113

2023-01022 CE 4377

Details and patient eligibility

About

The objective of the study is to investigate the long-term outcomes of minimally invasive liver surgery (robotic vs laparoscopic) for hepatocellular carcinoma patients of stage BCLC 0-A. Data from two tertiary centers for liver surgery will be retrospectively reviewed. Patients will be divided in two cohorts (robot; laparoscopy). The primary endpoint will be recurrence-free and overall survival; secondary endpoints were incidence, pattern, and treatment of recurrences.

Enrollment: 196 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing robotic and laparoscopic resections
• Histology-confirmed HCC of stage BCLC 0-A
• Preserved liver function (Child score A-B)
• Patients >18 years old

Exclusion criteria

• Hand-assisted procedures
• Non-elective surgery
• Intraoperative switch to locoregional therapies (like radiofrequency or microwave ablation)
• Non-histologically confirmed HCC
• Mixed hepato-cholangiocarcinoma.

Trial design

196 participants in 2 patient groups

Robotic liver resections

Treatment:

Procedure: Minimally invasive liver resection

Laparoscopic liver resection

Treatment:

Procedure: Minimally invasive liver resection