Role of Anterior Segment Optical Coherence Tomography in Infectious Keratitis

Minia University

Status: Completed

Conditions: Infective Keratitis

Treatments: Other: Optical coherence tomography

Study type: Observational

Funder types: Other

Identifiers

NCT04969640

43:6/2021

Details and patient eligibility

About

To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.

Full description

50 patients with proven infectious keratitis clinically will be included in the study.

The following will be performed for all patients in initial visit and follow up:

• Slit lamp examination and photography.

• Visual acuity assessment.

• Anterior segment optical coherence tomography.

  1. The central corneal thickness (CCT) (extracted from pachymetry map),
  2. Minimal corneal thickness (MCT) (extracted from pachymetry map)
  3. Corneal thickness at the site of the lesion (CTL) (extracted from pachymetry map or the sum of STL+ CETL)
  4. Stromal thickness at the center of the lesion (STL) stromal lesion (extracted from stromal map)
  5. Corneal epithelial thickness over the stromal lesion (CETL) at the center of the lesion (extracted from epithelial map)

Enrollment: 23 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

Exclusion criteria

• Cases with healed infectious keratitis.
• Cases presented from the start with severe corneal affection and melting.

Trial design

23 participants in 1 patient group

infective keratitis

Description:

50 cases with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

Treatment:

Other: Optical coherence tomography