Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn

Ankara University

Status: Completed

Conditions: Wet Lung

Study type: Observational

Funder types: Other

Identifiers

NCT01149928

08H3330006

Details and patient eligibility

About

In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the development of Transient Tachypnea of the Newborn (TTN), via their modulatory effect on epithelial sodium channels and Na-K-ATPase.

Enrollment: 70 patients

Sex: All

Ages: 34 to 40 weeks old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Gestation age > 34 weeks
• C/S delivered infants
• Parental consent form signed

Exclusion criteria

• Gestation age < 34 weeks
• Maternal conditions that compromised fetal well-being (hypertensive disorder, diabetes, chorioamnionitis)
• Intrauterine growth retardation
• Congenital malformations
• Absence of parental consent

Trial design

70 participants in 2 patient groups

C/S delivered, wet lung

C/S delivered, healthy infants