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Role of CT in Tetralogy of Fallot Diagnosis

A

Assiut University

Status

Not yet enrolling

Conditions

Cardiac CT TOF

Treatments

Device: Computed tomography

Study type

Observational

Funder types

Other

Identifiers

NCT07247435
Cardiac CT

Details and patient eligibility

About

To evaluate the role of MSCT in diagnosis and surgical planning in tetralogy of Fallot cases.

Full description

Role of Computed tomography (CT) : CT has become an indispensable imaging modality in the comprehensive evaluation and management of Tetralogy of Fallot (ToF). While echocardiography remains the initial diagnostic tool, CT offers unparalleled spatial resolution and the ability to generate high-quality, three-dimensional reconstructions of both intracardiac and extracardiac anatomy. This is particularly valuable for identifying associated anomalies such as major aortopulmonary collateral arteries (MAPCAs), anomalous coronary artery origins, and variations in pulmonary artery branching patterns that can significantly influence surgical decision-making. Preoperatively, CT enables precise assessment of the severity and extent of right ventricular outflow tract obstruction, ventricular septal defect morphology, and the relationship of the overriding aorta to the interventricular septum.

Overall, CT complements other imaging modalities by providing a fast, accurate, and comprehensive anatomical roadmap that guides surgical planning, informs long-term follow-up, and aids in the early detection of complications. Its role is particularly pronounced in complex and syndromic cases of ToF, where anatomical variations are more common and precise preoperative mapping is critical for successful outcomes.

Enrollment

37 estimated patients

Sex

All

Ages

Under 12 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

- patients aged 1 day up to 12 years Confirmed diagnosis of tetralogy of Fallot. Patients with tetralogy of Fallot as apart from genetic syndrome.

Exclusion criteria

  • Patients with other isolated congenital heart anomalies Previously operated cases of tetralogy of Fallot.

Trial contacts and locations

0

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Central trial contact

Benyamin Gaballah; Hassan Megaly, Professor

Data sourced from clinicaltrials.gov

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