Role of Dopamine Transporter in Glucose Control

Pusan National University

Status: Completed

Conditions: Obesity

Treatments: Other: Glucose injection/Normal saline injection

Study type: Interventional

Funder types: Other

Identifiers

NCT03466697

1707-019-057

Details and patient eligibility

About

Healthy subjects will be enrolled in this study. Each subject will be scanned twice with F18-FP-CIT PET which is commercially available. F18-FP-CIT reflects dopamine transporter availability of striatum. Before each PET scan, subject will be injected either glucose or normal saline. Therefore, PET scan will reflect the changes of dopamine transporter availability after the injection of glucose.

Enrollment: 40 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects

Exclusion criteria

• known neurologic disorder
• known drug addiction
• known endocrine disorder

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

40 participants in 1 patient group

Healthy subjects

Other group

Description:

All subjects will be injected twice for each visit (normal saline or glucose)

Treatment:

Other: Glucose injection/Normal saline injection