Role of EBUS-TBNA in Diagnosing TB in Mediastinal/Hilar Lymph Nodes

Centre Hospitalier Universitaire Saint Pierre

Status

Suspended

Conditions

Tuberculosis

Treatments

Procedure: EBUS-TBNA

Study type

Interventional

Funder types

Other

Identifiers

NCT01350674

B07620109427

AK/10-10-3949/67 (Other Identifier)

Details and patient eligibility

About

This is an observational prospective study. Role of EBUS-TBNA (endobronchial ultrasound transbronchial needle aspiration) is evaluated to diagnose tuberculosis in mediastinal and/or hilar lymph nodes.

The investigators analyse the specificity and sensibility of this technique to diagnose tuberculosis in mediastinal and/or hilar lymph nodes.

Patients with mediastinal and/or hilar lymph nodes on X-ray or CT thorax where a tuberculosis is the most probable cause and who have no parenchymal lesions suspected for tuberculosis and without other lymph nodes that are more easily accessible or palpable will be included in this study.

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients with enlarged mediastinal and/or hilar lymph nodes on chest CT highly suspicious of tuberculosis (suggestive clinical history, suggestive echographic findings ...) without pulmonary lesions suspicious for tuberculosis or in whom the first evaluation with sputum examination, classical bronchoscopy, induced sputum didn't result in any diagnosis.
patients aged 18 years or older
patients need to sign the consent form after reading the information form

Exclusion criteria

synchronic pulmonary lesions suspicious for tuberculosis or already proven tuberculosis by microscopic exam, PCR-technique and/or culture
other affected ganglionary sites more easily accessible (cervical, supraclavicular, axillary ... region)