Role of HVNI in Severe Chest Trauma

Assiut University

Status: Not yet enrolling

Conditions: Chest Trauma

Treatments: Device: High Velocity Nasal Insufflation

Study type: Interventional

Funder types: Other

Identifiers

NCT05692076

HVNI in severe chest trauma

Details and patient eligibility

About

to compare the respiratory complications in patient managed with high velocity nasal insufflation versus patients managed with conventional low flow oxygen in patients with severe chest trauma

Full description

• Chest trauma are associated with significant morbidity and mortality due to respiratory failure and pneumonia.
• The two main goals of therapy are pain management and pulmonary care and support. There is strong evidence for providing good analgesia to facilitate volume expansion treatment and chest physiotherapy, aiming for deep breathing and effective cough to reduce secretions and prevent the atelectasis.
• Oxygen supplementation is often included as supportive therapy added to bundles of care for patients of chest trauma with rib fractures.

High -velocity nasal insufflation (HVNI ) was first developed for neonates and has gained increasing use in adult patients for prevention and treatment of respiratory failure. High-flow humidified oxygen with flow rates from 30 to100 L/min with high fraction of inspired oxygen( FiO2) is able to be delivered. Positive end-expiratory pressure can be generated, preventing alveoli collapse. The washout of carbon dioxide (CO2)and replacement with enriched O2 purportedly decreases work of breathing and increases breathing effectiveness.

• Routine tests for chest injuries include chest X-rays and computed tomography (CT) scans. Ultrasound has the advantages of being inexpensive, readily available and being free of ionizing radiation .
• In thoracic trauma cases, ultrasonography of the lungs is valuable for evaluating various chest diseases, including chest wall haematoma and fractures, pleural cavity involvement with pleural effusion, haemothorax, and pneumothorax. The ultrasound can also assess the reduce in lung aeration by changing the lung surface and generating distinct patterns as in pulmonary contusions and compression atelectasis.

Enrollment: 86 estimated patients

Sex: All

Ages: 15 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chest trauma patients with lung injury confirmed by ct imaging

  • the age from 15-55 years old
  • No indication of mechanical ventilation at the time of admission to the intensive care unit

Exclusion criteria

• • Patients < 15years old

  • requiring endotracheal intubation and mechanical ventilation immediately on admission for any cause
  • facial fractures or base of skull fractures
  • Who did not receive a chest computed tomography (CT) scan
  • Glasgow Coma Scale <10
  • Massive surgical emphysema
  • COPD Patients ( chronic obstructive pulmonary disease )

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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86 participants in 2 patient groups

HVNI group

Experimental group

Description:

Patients will receive high velocity nasal insufflation therapy

Treatment:

Device: High Velocity Nasal Insufflation

Control group

Other group

Description:

Patient will receive conventional oxygen therapy via nasal prongs , normal oxygen mask or venturi mask

Treatment:

Device: High Velocity Nasal Insufflation