Role of Hyaluronic Acid in Bone Healing After Dental Extraction

Damascus University

Status: Completed

Conditions: Patients With Dental Extraction

Treatments: Drug: Hyaluronic Acid

Study type: Interventional

Funder types: Other

Identifiers

NCT02330822

UDDS-OMFS-01-2015

Details and patient eligibility

About

This is a randomized controlled trial with a split mouth design. Patients with an indication of lower dental extraction will be asked to join this research project at the Department of Oral and Maxillofacial Surgery at University of Damascus Dental School. Each patient whose case requires bilateral extraction, one side will serve as an experimental side, whereas the other side will serve as a control.

Participants should have symmetric teeth that need extraction in the lower jaw. Hyaluronic acid will be injected following extraction in one of the two sides with random allocation.

cone-beam computerized tomography (CBCT) images will be taken for each participant immediately post-extraction and at six months post-operatively.

Full description

I- Clinical examination variables:

Buccolingual distance and distomesial distance will be measured for each participant at 2 assessment times: directly post-extraction and six months post-extraction.

II- Radiographic examination variables:

Linear measurements Vertical bone fill Bone mineral density

Enrollment: 20 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-60 years old
• Symmetric teeth requiring extraction in the lower jaw
• Systematically healthy

Exclusion criteria

• Smokers
• Pregnancy (for female participants)
• Diabetic patients
• Patients with metabolic problems

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Hyaluronic Acid Group

Experimental group

Description:

In this Group, Hyaluronic acid will be injected following extraction.

Treatment:

Drug: Hyaluronic Acid

Traditional Extraction Group

No Intervention group

Description:

In this group, traditional extraction procedures will be followed.