Role of Intra-Operative Aspiration in Distended GB in LC

Aswan University

Status and phase

Completed

Phase 3

Conditions

Acute Calculous Cholecystitis

Gallbladder Mucocele

Gallbladder Empyema

Treatments

Procedure: Laparoscopic needle

Study type

Interventional

Funder types

Other

Identifiers

NCT07378410

Asw.Uni./978/9/24

Details and patient eligibility

About

Laparoscopic cholecystectomy (LC) is a standard procedure for gallstones and the standard surgical approach for acute calcular cholecystitis, superseding open cholecystectomy for gallbladder (GB) pathologies. Despite this progress, mortality rates in high-risk cohorts remain substantial, ranging between 3.7% and 41.0%. Moreover, the recommended modality for mucocele which is defined as distension and marked dilatation of the GB associated with dysfunction is LC.

The routine aspiration showed significant less percentage of GB perforation during surgery with similarity for other factors . However, routine aspiration of the GB during uncomplicated LC is considered an unnecessary intervention and therefore not recommended as a routine practice.

Accidental GB perforation occurs in about 20% of laparoscopic cholecystectomies, and bile contamination in the abdominal cavity can cause SSI and lead to the formation of a residual abscess or wound infection.

Grasping a thick and distended GB is one of the most common technical difficulties of laparoscopic cholecystectomy in acute cholecystitis. If the GB is distended it should be decompressed it to avoid conversion to open due to bile duct injury or perforation with spillage of bile and gallstones previously, authors had advocated conversion if iatrogenic perforation occurred.

Full description

This study was conducted on patients with symptomatic calcular cholecystitis presented to Aswan university hospital.

The following parameters were measured intraoperative difficulty.

Operative time
Incidence of biliary tree injury
Higher surgeon consultation
Conversion into open surgery All groups were followed up for 30 days period for post-operative complication clinically and by sonar.
Wound infection
Liver bed bleeding
Collection in the liver bed
Peritonitis
Hospital stays.

Enrollment

70 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient with calcular cholecystitis, GB mucocele or GB empyema
Distended gallbladder: shiny, over distended, long, difficult to grasp and manipulate gallbladder.
Acute or chronic calcular cholecystitis

Exclusion criteria