Role of K+ and Ca2+ in Development of Muscle Fatigue

University of Copenhagen

Status: Completed

Conditions: Skeletal Muscle Fatigue in Humans

Treatments: Drug: Terbutaline; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02712658

MIK

Details and patient eligibility

About

The aim of the study is to investigate the role of K+ and Ca2+ in development of muscle fatigue in trained young men.

Enrollment: 10 patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• physical active healthy men
• aged 18-40 years

Exclusion criteria

• smokers
• allergy towards terbutaline
• chronic disease

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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10 participants in 2 patient groups, including a placebo group

terbutaline

Active Comparator group

Description:

terbutaline is administered by injection (0.25-0.5 mg Bricanyl, AstraZeneca diluted in 9 ml isotonic saline)

Treatment:

Drug: Terbutaline

Placebo

Placebo Comparator group

Description:

placebo is administered as isotonic saline (10 ml)

Treatment:

Drug: Placebo