Role of Macrophage Migration Inhibitory Factor (MIF) in Heart Failure

University Hospital Essen

Status: Completed

Conditions: Heart Diseases

Treatments: Diagnostic Test: MIF ELISA

Study type: Observational

Funder types: Other

Identifiers

NCT03232671

15-6529-BO

Details and patient eligibility

About

Evaluating the additional value of Macrophage Migration Inhibitory factor (MIF) in cardiovascular diseases when assessed in clinical routine.

Enrollment: 180 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All patients presenting with symptoms of heart failure to the West-German Heart and Vascular Center according to the definition of the ESC 2016.

• Patients fulfilling criteria for the diagnosis of HFrEF
• Patients fulfilling criteria for the diagnosis of HFpEF
• Patients fulfilling criteria for the diagnosis of HFmrEF
• Patients presenting with dyspnea according to the NYHA classification I-IV, elevated BNP/NT-proBNP levels and echocardiographic findings of heart failure.

Exclusion criteria

• Age < 18 years
• Patients with symptoms of heart failure without fulfilling the criteria of the ESC guidelines 2016
• Denial to participate