Role of Mega Dose of Vitamin C in Critical COVID-19 Patients

University of Lahore

Status: Completed

Conditions: Corona Virus Infection

Treatments: Drug: Vitamin C

Study type: Interventional

Funder types: Other

Identifiers

NCT04682574

IRBEC/BIH/09-2020

Details and patient eligibility

About

Vitamin C (ascorbic acid) is a water-soluble vitamin having anti-inflammatory, immunomodulatory, anti-oxidative, antithrombotic and antiviral properties. Considering these effects vitamin C should have beneficial impact in patients suffering from sepsis and acute respiratory distress syndrome (ARDS). The current study is designed to assess the beneficial effects of Vitamin C in COVID-19 infected patients.

Enrollment: 278 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

critically ill patients admitted in ICU

Exclusion criteria

allergic to Vitamin C didnt given the consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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278 participants in 2 patient groups

vitamin C

Active Comparator group

Description:

The dose would be 30 grams a day (10 grams TDS) for 3 days with standard treatment

Treatment:

Drug: Vitamin C

Placebo

No Intervention group

Description:

Distill water in the same dose with same standard treatment