Role of MSCT Volumetry in Assessment of Brain Atrophy in Septic Patients

Assiut University

Status: Not yet enrolling

Conditions: Sepsis-Associated Encephalopathy

Treatments: Device: MSCT

Study type: Observational

Funder types: Other

Identifiers

NCT06112119

sepsis and brain atrophy

Details and patient eligibility

About

assessment of brain atrophy associated with septic ICU patients by using MSCT Volumetry

Full description

Sepsis is the leading cause of admission to ICU , the number of patients who survive and discharge from ICU has also increased due to technological advances in ICU however quality of life of these patients after ICU discharge is lower than that of healthy people of a similar age, in particular Sepsis associated encephalopathy associated with brain dysfunction.

We hypothesized that brain damage including brain volume reduction that ocurre in acute phase of Sepsis using CT scan and there finding " relationship to risk factor and outcome".

We compared head CT finding at time of admission with those obtained during the course of the treatment

Enrollment: 55 estimated patients

Sex: All

Ages: 16 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients >16years old with sepsis associated with disturbance in conscious level admitted to ICU

Exclusion criteria

• Age< 16y Brain death Hematological disease Malignant disease Hypoxemia Error in automatic tissue classification Motion artifac

Trial design

55 participants in 1 patient group

cohort

Description:

patients \>16y with sepsis associated with disturbance in conscious level, the first braun CT scan will be routinely performed on admission, the second further brain CT Scan will be obtained whenever prolonged disturbance of consciousness will be detected.

Treatment:

Device: MSCT