Role of Novel ILR in the Management of PVCs

Kansas City Heart Rhythm Research Foundation

Status: Enrolling

Conditions: Myocarditis; PVC - Premature Ventricular Contraction

Treatments: Other: Monitoring of patients presenting with PVCs

Study type: Observational

Funder types: Other

Identifiers

NCT06060548

KCHRF-ILR_PVC-0011

Details and patient eligibility

About

This prospective, observational study is a single center clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Subjects will be followed through 12 months. The study will enroll approximately 50 patients.

Full description

This study is intended to monitor patients presenting with Premature Ventricular Contractions (PVCs) and ventricular arrhythmias using implantable loop recorders (ILRs) from the time of their initial presentation of PVCs to assess for the incidence of all cardiac arrhythmias detected with long term monitoring in this population. It is also intended to evaluate for clinical, biomarker and radiological evidence of myocarditis in this cohort to understand association with incident arrhythmias and understand the role of implantable loop recorders (ILRs)in managing these patients.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients > 18 years of age
• Have a Medtronic LINQ II ILR
• Willing and able to give written informed consent

Exclusion criteria

• History of myocardial infarction
• Significant flow-limiting coronary artery disease (≥50% stenosis) on invasive coronary angiography or Computed tomography angiography (CTA).
• History of cardiac arrest
• With existing implantable defibrillators
• Currently pregnant

Trial design

50 participants in 1 patient group

Patients with PVCs

Description:

Patients referred for management of symptomatic or asymptomatic PVCs. Patients presenting with PVCs and ventricular arrhythmias will be monitored using ILRs from the time of their initial presentation of PVCs.

Treatment:

Other: Monitoring of patients presenting with PVCs