Role of Oral Glutathione in Skin Whitening

Chulalongkorn University

Status and phase: Completed; Phase 1

Conditions: Skin Whitening

Treatments: Drug: placebo; Drug: glutathione

Study type: Interventional

Funder types: Other

Identifiers

NCT01016080

COA840/2008

Details and patient eligibility

About

Oral and intravenous glutathione have been used widely to whiten the skin. The investigators tested this hypothesis by giving oral glutathione for 4 weeks to medical students.

Enrollment: 60 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy medical students

Exclusion criteria

• history of skin cancer, especially melanoma
• consumption of any preparations containing glutathione within 1 month of enrollment
• pigmentary disorders or any dermatoses

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups, including a placebo group

oral glutathione

Active Comparator group

Description:

glutathione, 500 mg, taken orally twice daily

Treatment:

Drug: glutathione

placebo capsules

Placebo Comparator group

Description:

identical-appearing placebo capsules

Treatment:

Drug: placebo