Role of Regular Surveillance on Maintenance of Patency of an Arteriovenous Access

Assiut University

Status: Unknown

Conditions: Hemodialysis Access Failure

Treatments: Device: duplex ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT04098159

Surveillance of an A-V access

Details and patient eligibility

About

Chronic Kidney disease (CKD) is a worldwide public health problem that classified into five stages (1). End stage renal disease (CDK stage 5) patients require a well-functioning vascular access (VA) for successful hemodialysis treatment (2). Types of VA include arteriovenous fistulae (AVFs) and arteriovenous grafts (AVGs). A vascular access is liable to early or late complications, and ultimately access failure. A meta-analysis showed that a 17% mean early access failure However recent studies have shown higher failure rates of up to 46%, with one year patencies between 52% to 83% (3). Low VA flow, thrombosis and loss of patency may result in under-dialysis that leads to increased morbidity, mortality and healthcare expenditure (4). In the majority of VAs, stenoses develop over variable intervals causing VA thrombosis and failure (5). If early detected and corrected, VA function and patency can be preserved and under-dialysis can be minimized or avoided. The aim of this study is to find out the role of periodic surveillance of VA in the detection of VA dysfunction and correctable lesions that may necessitate pre-emptive interventions to maintain VA patency and prevent VA loss

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ESRD Patients have functioning or failing VAs (AVFs or AVGs).

Exclusion criteria

• ESRD patients have infected or failed VAs .
• patientrefusal .

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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200 participants in 1 patient group

ESRD Patients have functioning or failing VAs (AVFs or AVGs).

Experimental group

Treatment:

Device: duplex ultrasound