Role of REM Sleep Alterations in Post Operative Delirium After Cardiac Surgery

Poitiers University Hospital

Status: Unknown

Conditions: Delirium Symptoms

Treatments: Procedure: Polysomnography

Study type: Interventional

Funder types: Other

Identifiers

NCT02801318

DELI-SLEEP

Details and patient eligibility

About

Acute confusional states known as delirium frequently occur in Intensive Care Units (ICU), mostly after cardiac surgery, leading to serious consequences. Sleep deprivation has been described in ICU patients and is considered as a risk factor for delirium but its role is still unknown. It is therefore essential to identify whether sleep deprivation and more specifically REM sleep alterations could facilitate occurence of delirium in ICU.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who had a cardiac surgery with extracorporeal circulation.
• Patients who were extubated at Day 0.
• Patients without any operation or anesthetic complication.
• Patients who speak French.
• Patients without TNC at Day 1.
• Patients who had completed the questionnaires before operation.

Exclusion criteria

• Age < 18 years old.
• Delirium at Day 1.
• Central nervous system pathology or psychiatric pathology known and treated.
• Concomitant use of neuropsychiatric treatment before surgery that interferes with sleep.
• Clinical condition alteration before polysomnography exam.
• Continue sedation required before Day 3 polysomnography exam.
• Agitation or clinical alteration that did not allow Day 3 polysomnography exam.

Trial design

60 participants in 1 patient group

Polysomnography

Other group

Treatment:

Procedure: Polysomnography