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Role of the Radiologist in Management of Pulsatile Tinnitus

M

Mohab Mohammed

Status

Unknown

Conditions

Pulsatile Tinnitus (Diagnosis)

Treatments

Device: Colour doppler,MSCT,MRI

Study type

Interventional

Funder types

Other

Identifiers

NCT05338684
Radiology role in tinnitus

Details and patient eligibility

About

The aim of this study is to detect the role of interventional radiology in management of Pulsatile tinnitus and to detect the best imaging modality for Diagnosis.

Full description

Tinnitus is a broad and complex subject concerning a symptom rather than a syndrome or a disease (1 ),New studies indicate that prevalence of tinnitus is 14.5% among those less than 40 years old and 17.5 - 35% among age over 40 years Old( 2-3 ). Vascular tinnitus causes are multiple , Arterial causes like Atherosclerosis , Fibromuscular dysplasia or Dissection of the carotid or vertebral artery , Arteriovenous causes like Cerebral head and neck arteriovenous malformation , Dural arteriovenous fistula and Carotid cavernous fistula Venous like Systemic diseases with hyperdynamic circulation . Chronic anemia, pregnancy, thyrotoxicosis , Idiopathic intracranial hypertension and Dural venous sinus stenosis , Tumors also like Paraganglioma which Some authors believe that para-gangliomas are the most common cause of vascular tinnitus and Vascular metastasis And other Miscellaneous Causes like Paget's disease m Otosclerosis or Otomastoiditis , but others see dural arteriovenous fistula (AVF) ,idiopathicvenous tinnitus, or idiopathic intracranial hypertension the most common causes. (4 - 9) , Also One of the Most important Arterial causes is Atherosclerosis , Atherosclerotic plaques ma produce turbulence of carotid flow and occasionally cause pulsatile tinnitus (10 ) , FMD ( Fibromuscular Dysplasia ) seen in 0.5% to0.6% of carotid angiograms and autopsies, is the second most common cause of extracranial carotid narrowing (11) information obtained from both CT and MRI is complementary In some casesThe angiographic findings may include luminal stenosis, abrupt reconstitution of the lumen, dissecting aneurysm, intimal flap, slow flow, occlusion, and distal emboli (12-15)

Enrollment

50 estimated patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients with pulsatile tinnitus of unknown origin referred by a physician to diagnostic radiology to be assessed by imaging will be included in the study.
  • Patient's with clinical diagnosed pulsatile tinnitus.
  • patient refused surgical intervention.

Exclusion criteria

  • History of allergy to the contrast media , Contraindication to MRI and Refusal to sign a consent
  • Pregnant women
  • patients with atherosclerosis cause only or vascular loop more than 50% in internal auditory canal

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

50 participants in 1 patient group

diagnostic catheter intervention then therapeutic if indicated
Experimental group
Treatment:
Device: Colour doppler,MSCT,MRI

Trial contacts and locations

0

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Central trial contact

Hany Mohamed, Prof; Mohab Mohammed, Dem

Data sourced from clinicaltrials.gov

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