Role of Two Rehabilitative Treatments and Diet in the Modulation of Inflammation in Patients With Knee Prosthesis.

Presidio Ospedaliero di Asiago

Status: Completed

Conditions: Knee Pain Swelling

Treatments: Procedure: Lymphatic drainage

Study type: Interventional

Funder types: Other

Identifiers

NCT04580069

POAsiago

Details and patient eligibility

About

The investigators studied the influence of two aproved rehabilitative treatments, connective tissue techniques and lymphatic drainage, on acute inflammation markers. Furthermore, the role of mediterranean diet on the same values was investigated in the first postoperative period

Full description

The main objective of this study is to demonstrate the effectiveness of lymphatic drainage and connective tissue techniques in modulating systemic inflammation. Another objective is to evaluate the existence, at baseline, of a correlation between the inflammation indices and the level of adherence to the Mediterranean diet.

Methods. 34 patients were recruited, and divided into three groups. The control group followed the normal rehabilitation protocol. The other two groups were subjected, in addition to the standard treatment, to manual lymphatic drainage treatment or connective tissue techniques. The outcomes (PCR, ESR, Oedema) were recorded in three stages: upon entering the hospital, 1 week after entry and at follow-up 21 days after surgery.

Enrollment: 34 patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

• 50<age<80 years
• Bicompartmental knee arthroplasty
• Weight bearing 7 days after surgery
• Transfusions according to hospital protocol
• Alteration of the indices at T0
• Standard analgesic therapy

Exclusion Criteria:

• Joint replacements from other Units
• Inflammatory arthropathies
• Autoimmune / rheumatic diseases
• Obesity
• Diabetes mellitus
• Infections

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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34 participants in 3 patient groups

Lymphatic drainage

Experimental group

Description:

Patients subjected to manual lymphatic drainage

Treatment:

Procedure: Lymphatic drainage

Connective tissue

Experimental group

Description:

Patients subjected to connective tissue massage

Treatment:

Procedure: Lymphatic drainage

control group

Active Comparator group

Description:

Subjects hat followed standard rehabilitative treatment

Treatment:

Procedure: Lymphatic drainage