Role of Wound Irrigation After Appendectomy

Mansoura University

Status: Completed

Conditions: Appendicitis

Treatments: Procedure: Irrigation

Study type: Interventional

Funder types: Other

Identifiers

NCT03773224

mansoura67

Details and patient eligibility

About

Surgical site infection is a common problem after open appendectomy. Irrigation of the surgical wound by topical antibiotics has been devised as a measure to reduce the incidence of wound infection. The present trial aims to assess the efficacy of layer-by-layer wound irrigation with gentamicin-saline solution in prevention of superficial surgical site infection after open appendectomy for acute uncomplicated appendicitis.

Enrollment: 179 patients

Sex: All

Ages: 16 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients of both genders aging between 18 and 65 years who present with acute appendicitis.
• Patients with perforated appendicitis will be also included.

Exclusion criteria

• Patients with appendicular mass, appendicular abscess, generalized peritonitis.
• Patients with other causes of acute abdomen as revealed intraoperatively.
• Patients taking long course of steroid therapy or immunosuppressive treatment,
• Patients unwilling to participate in the trial.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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179 participants in 2 patient groups

Irrigation

Active Comparator group

Description:

Layer by layer irrigation of the surgical wound with gentamicin-saline solution

Treatment:

Procedure: Irrigation

Control

No Intervention group

Description:

The surgical wound is closed layer by layer without irrigation