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Rosemary Infusion for Hypertension With Hypertriglyceridemia

A

awatef Sassi

Status

Completed

Conditions

Hypertension With Hypertriglyceridemia

Treatments

Dietary Supplement: rosemary infusion
Dietary Supplement: Rosemary infusion

Study type

Interventional

Funder types

Other

Identifiers

NCT07352124
TGhypertension

Details and patient eligibility

About

This study aimed to evaluate the effects of daily rosemary infusion consumption on blood pressure and lipid profile in patients with mild hypertension, stratified by triglyceride status.

This 6-week open-label interventional study enrolled 47 patients with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg). Participants were stratified into two groups: normal triglycerides, TG <1.7 mmol/L, n=22 and high triglycerides, TG ≥1.7 mmol/L, n=25. Blood pressure was assessed using 24-hour ambulatory monitoring (Holter) at baseline and day 45. Comprehensive biochemical analysis included lipid profile, hepatic and renal function markers, and inflammatory parameters.

Enrollment

47 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Participants of both sexes, aged 18 years and older, were included in the study. The inclusion criteria were: (1) Presence of mild hypertension defined as systolic blood pressure (SBP) of 140-159 mmHg and/or diastolic blood pressure (DBP) of 90-99 mmHg according to the 2018 ESC/ESH guidelines(Williams et al., 2018); (2) No use of medications or dietary supplements for other health conditions.

Exclusion criteria

Participants were excluded if they had renal failure, autoimmune diseases, major gastrointestinal disorders, or a history of cardiovascular disease. Other exclusion criteria included current or past use of medications known or suspected to influence blood pressure or metabolic parameters

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

47 participants in 2 patient groups

Groupe triglycérides normaux TG < 1,7 mmol/L n = 22
Experimental group
Treatment:
Dietary Supplement: Rosemary infusion
TG ≥ 1,7 mmol/L n = 25
Experimental group
Treatment:
Dietary Supplement: rosemary infusion

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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