Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision

University of Malaya

Status: Completed

Conditions: Pterygium

Treatments: Procedure: Full Conjunctival Graft; Procedure: Rotational Narrow Strip Conjunctival Graft

Study type: Interventional

Funder types: Other

Identifiers

NCT01083927

UMERC003

Details and patient eligibility

About

To compare the efficacy of rotational narrow strip conjunctival graft to full conjunctival graft in primary pterygium excision. Risk analysis of factors that may affects the recurrence rate.

Full description

Pterygium is a raised, wing-shaped growth of fibrovascular tissue that extends horizontally from the bulbar conjunctiva, crossing the limbus, and onto the cornea. It is a common ocular surface disease in Malaysia.

Pterygium can cause chronic ocular irritation, redness, tearing, visual impairment and poor cosmesis. Treatment of symptomatic pterygium remains surgical. Surgery should achieve low recurrence rate and acceptable cosmesis. Various surgical techniques had been described with variable success.

In this study, we compared the efficacy of Rotational Narrow Strip Conjunctival Graft with the conventional full conjunctival graft in pterygium excision. Patient will be follow up for a year after pterygium surgery. Outcome will be recurrence rate between the two groups at one year. Risk analysis of certain factors that affects the recurrence rate will be discussed.

Enrollment: 94 patients

Sex: All

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Significant and symptomatic primary pterygium clinically requiring excision
2. Willingness to participate in research project and to attend research time

Exclusion criteria

1. Age < 21 years
2. Glaucoma in the study eye
3. Other concurrent ocular surface pathology
4. Infection of the ocular surface
5. Poor general health

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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94 participants in 2 patient groups

Rotational Narrow Strip Graft

Active Comparator group

Description:

Technique of surgery

Treatment:

Procedure: Rotational Narrow Strip Conjunctival Graft

Full Graft

Active Comparator group

Description:

Surgical technique

Treatment:

Procedure: Full Conjunctival Graft