Routine Screening for Eosinophilic Esophagitis in Patients Presenting With Dysphagia

San Antonio Uniformed Services Health Education Consortium

Status: Unknown

Conditions: Dysphagia

Study type: Observational

Funder types: Other U.S. Federal agency

Identifiers

NCT01028235

FWH20060112H

Details and patient eligibility

About

The purpose of this study is to identify the prevalence of pathologic eosinophilic esophagitis (EoE) in the cohort of adult patients who present for specialty care in the gastroenterology clinics with complaint of difficulty swallowing (dysphagia). From this, the investigators will make recommendations regarding routine screening for the diagnosis in this cohort. The prevalence of EoE in patients presenting for specialty care in the gastroenterology clinics with the complaint of dysphagia is great enough that the diagnosis should be routinely screened against in this cohort.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age > 18
• complaint of dysphagia

Exclusion criteria

• pregnancy
• age <18
• on inhaled steroids within the last 30 days
• on systemic steroids in the last 30 days
• known diagnosis of Eosinophilic Esophagitis
• obvious obstructive etiology found at endoscopy
• increased risk of bleeding (on blood thinners or anti-platelet agents other than aspirin)

Trial design

150 participants in 2 patient groups

Obstructive Dysphagia

Description:

Patients who complained of dysphagia, which had an obstructive etiology for their symptoms at the time of endoscopy (ring, mass, stricture, etc)

Non-obstructive Dysphagia

Description:

Patients whose endoscopy was normal and without any obvious etiology for their symptoms noted.