rTMS for Adults With Autistic Spectrum Disorder

Chang Gung Medical Foundation

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Autism

Treatments: Device: repetitive TMS

Study type: Interventional

Funder types: Other

Identifiers

NCT01918787

NSC 100-2314-B-182A-075 (Other Identifier)

100-2985C

Details and patient eligibility

About

rTMS over dorsolateral prefrontal cortex is effective in reducing repetitive behaviors in adults with autistic spectrum disorder rTMS over posterior superior temporal sulcus is effective in improving social ability in adults with autistic spectrum disorder

Full description

First, we will apply one session intermittent theta burst stimulation over dorsolateral prefrontal cortex, posterior superior temporal sulcus and inion as control with one week interval in adults with autism spectrum disorder. Second, we will apply 5 sessions intermittent theta burst stimulation within one week over dorsolateral prefrontal cortex or posterior temporal sulcus depending on the results of our first phases.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adults with autistic spectrum disorder

Exclusion criteria

• schizophrenia
• bipolar affective disorder
• major depressive disorder
• any systemic disease especially epilepsy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

repetitive TMS

Experimental group

Description:

repetitive TMS over dorsolateral prefrontal cortex, posterior superior temporal sulcus and inion as control

Treatment:

Device: repetitive TMS