Rudolph: Nasal Microbiota With Red and Sore Nose

Kimberly-Clark

Status: Completed

Conditions: Dermatitis

Treatments: Other: Rhinovirus Challenge

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03073837

500-16-0006

Details and patient eligibility

About

This pilot study will utilize the experimental rhinovirus infection model to study changes in skin microbiota in relation to skin erythema and soreness.

Enrollment: 10 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• self reported proneness to developing symptoms of nose redness and/or soreness
• sero-negative to HRV-16 at screening

Exclusion criteria

• confirmed or self-reported allergic rhinitis
• history of nasal or otologic surgery
• use of anti-inflammatory medication, recent antibiotics or anti-histamines

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Rhinovirus Challenge

Other group

Description:

Challenge with HRV-16

Treatment:

Other: Rhinovirus Challenge