S1119 Peruvian H. Pylori Water Contamination Study

SWOG Cancer Research Network

Status: Completed

Conditions: Helicobacter Pylori Infection

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT01512875

S1119

Details and patient eligibility

About

The objective of this study is to elucidate the role of drinking water derived from the public source in Lima, Peru and transmission of H. pylori infection using genotypic techniques.

Full description

The objective of this study is to detect the presence of Helicobacter Pylori in the drinking water derived from the public network by molecular and genomic techniques in districts of Lima (Brena, Chorrillos, Comas, El Agustino, La Victoria, Lince, Los Olivos, Miraflores, Puente Piedra, Rimac, San Isidro, San Juan de Lurigancho, San Martin de Porres, Villa El Salvador, and Villa Maria del Triunfo) with high and low incidence of gastric carcinoma. The secondary objective of this study is to establish correlations between the findings in water and those of the stomach of patients with symptoms of dyspepsia who live in those districts.

Enrollment: 107 patients

Sex: All

Ages: 21 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adults between the ages of 21-70 years old who have lived for more than 10 years in the Lima districts listed in protocol,
• who have a biopsy proven diagnosis of infection by H. pylori.
• participants must be in good general condition, mentally competent and able to provide informed consent;
• must not show evidence of dehydration or jaundice;
• must be willing to complete the patient questionnaires.
• participants must not have known allergies to any of the antibiotics used in the study.

Exclusion criteria

• pregnancy

Trial design

107 participants in 1 patient group

biopsy proven H. pylori

Description:

Patient must have lived in the districts of Lima, Peru listed in the protocol.