Safe Pregnancy by Infectious Disease Control

NICHD Global Network for Women's and Children's Health

Status: Completed

Conditions: Malaria; Pregnancy

Study type: Observational

Funder types: Other; NETWORK; NIH

Identifiers

NCT00489619

U01HD043475 (U.S. NIH Grant/Contract)

GN 02 - Pilot

Details and patient eligibility

About

Malaria and sexually transmitted infections (STIs) are common in pregnant women in Africa and are important preventable causes of poor birth outcomes and maternal and infant mortality. This study investigated baseline characteristics of the population including: rates of STIs including HIV, prevalence of malaria and tuberculosis (TB) and resistance to common antimalarial drugs.

Full description

A cross-sectional observational study was conducted with 2008 pregnant women attending either Binza or Kingasani Maternity clinics in Kinshasa, DRC to determine baseline rates of STIs, TB and malaria. Data was collected for sample size calculation in a larger STI/Malaria and TB randomized controlled trial.

Enrollment: 2,008 patients

Sex: Female

Ages: 15+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• older than or equal to 15 years of age
• pregnant
• presenting for antenatal care at one of the two target maternities for the first time during the current pregnancy
• willing to provide informed consent

Exclusion criteria

• refusal to participate in the HIV voluntary and counseling program at the maternity center or refusal to share HIV results with the study staff.