Safe Use of CPAP and PEEP During Induction of General Anesthesia

Region Västmanland

Status

Completed

Conditions

General Anesthesia

Treatments

Procedure: Pressure controlled ventilation with PEEP

Procedure: Manual ventilation without PEEP

Study type

Interventional

Funder types

Other

Identifiers

NCT04271683

EPM 2019-05092

Details and patient eligibility

About

The study compares the safety of using pressure controlled ventilation with a positive end-expiratory pressure (PEEP) during induction of general anaesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.

Full description

Using a continuous positive pressure (CPAP) during preoxygenation, followed by pressure controlled ventilation with PEEP after apnoea during induction of general anesthesia, might offer several benefits but safety issues needs more investigation. This study compares the safety of using pressure controlled with PEEP during induction of general anesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.

Enrollment

70 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Normal or overweight patients scheduled for day case surgery in general anesthesia.
American Society of Anesthesiologists functional class I-III.
Body Mass Index 18.5-30.

Exclusion criteria

Increased risk of regurgitation of gastric content.
Symptomatic asthma, COPD or heart failure.
Peripheral oxygen saturation (SpO2) breathing air <94 %
Anticipated difficult airway.
Beard.
Anatomical features making it difficult to keep a tight seal during maskventilation.