Safety and Effectiveness of Ticagrelor in Patients Undergoing Carotid Stenting

Assiut University

Status and phase: Unknown; Phase 1

Conditions: Carotid Stenosis

Treatments: Drug: Ticagrelor; Procedure: Carotid stenting; Drug: Clopidogrel

Study type: Interventional

Funder types: Other

Identifiers

NCT04091074

Ticagrelor in carotid stenting

Details and patient eligibility

About

patients undergoing carotid stenting take dual anti platelet therapy to prevent thrombotic complications usually used drugs are aspirin plus clopidogrel but there are patients not respond so ticagrelor may be an effective and safe alternative

Enrollment: 26 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Ischemis stroke of both sex.
2. More than 18 years.
3. Accepting all study requirements.

Exclusion criteria

1. Refuse to comply with all study requirements.
2. bleeding tendency or liver diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

26 participants in 2 patient groups

aspirin + ticagrelor before carotid stenting

Active Comparator group

Description:

patients undergoing carotid stenting take aspirin 150 mg + ticagrelor 90mg for 15 days before carotid stenting

Treatment:

Drug: Ticagrelor

Procedure: Carotid stenting

aspirin + clopidogrel before carotid stenting

Active Comparator group

Description:

patients undergoing carotid stenting take aspirin 150 mg + clopidogrel 75 mg for 15 days before carotid stenting

Treatment:

Drug: Clopidogrel

Procedure: Carotid stenting