Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma

Alcon

Status and phase: Completed; Phase 2

Conditions: Open-angle Glaucoma

Treatments: Drug: Anecortave Acetate Sterile Suspension, 30 mg/mL; Other: Anecortave Acetate Vehicle

Study type: Interventional

Funder types: Industry

Identifiers

NCT00451152

C-06-19

Details and patient eligibility

About

The purpose of this study was to evaluate the safety and intraocular pressure (IOP)-lowering efficacy of anecortave acetate for treatment of elevated IOP in patients with open-angle glaucoma.

Enrollment: 89 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of open-angle glaucoma;
• Other protocol-defined inclusion criteria may apply.

Exclusion criteria

• Pseudoexfoliation;
• Pigment dispersion component;
• Other protocol-defined exclusion criteria may apply.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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89 participants in 2 patient groups, including a placebo group

Anecortave Acetate Depot

Experimental group

Treatment:

Drug: Anecortave Acetate Sterile Suspension, 30 mg/mL

Anecortave Acetate Vehicle

Placebo Comparator group

Treatment:

Other: Anecortave Acetate Vehicle