Safety and Efficacy of High Flow Nasal Canula in Patients With Mild Hypercapnia

Mansoura University

Status: Completed

Conditions: Hypercapnia

Treatments: Device: high flow nasal canula

Study type: Interventional

Funder types: Other

Identifiers

NCT05948527

R.22.12.1978.R1.R2

Details and patient eligibility

About

Evaluate safety and efficacy of application ( high flow nasal canula) in cases with mild hypercapnia, included 30 patients who were hospitalized in Mansoura University chest department with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30) of different pulmonary disease categories (Chronic obstructive pulmonary disease acute exacerbation, pneumonia, Interstitial lung diseases, etc).

Enrollment: 30 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with mild Hypercapnia

Exclusion criteria

• Excluded cases had age less than 18 years or pediatric group .
• patients with their mental state altered, confused, comatose, severe agitation or non cooperative
• Cases with moderate or severe Hypercapnia
• cases in need for immediate invasive mechanical ventilation
• cases with respiratory rate more than 35 breath per minute.
• cases with Respiratory exhaustion , fatigue , excess use of respiratory accessory muscles
• Shock , hemodynamic instability, post arrest cases,
• cases with facial trauma or severe nasal deformity,
• Patients with sleep breathing disorders or upper airway obstruction
• patients with history of home ventilation prior admission

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30)

Experimental group

Description:

with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30) of different pulmonary disorders

Treatment:

Device: high flow nasal canula