Safety and Tolerability of MK0773 in Healthy Older Men (0773-004)
Status and phase
Completed
Phase 1
Conditions
Healthy
Treatments
Drug: Comparator: placebo injection
Drug: MK0773
Drug: Comparator: testosterone enanthate
Drug: Comparator: placebo oral tablet
Details and patient eligibility
About
This study will assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of MK0773 in healthy older men.
Enrollment
68 patients
Sex
Male
Ages
50 to 75 years old
Volunteers
Accepts Healthy Volunteers
Inclusion criteria
- Subject is in good general health
- Subject agrees to avoid excess alcohol and strenuous physical activity during the study
- Subject who is sexually active with partners of reproductive potential agrees to use two forms of appropriate contraception during the study
Exclusion criteria
- Subject has significant drug allergies
- Subject has donated blood within the last 8 weeks or has taken an investigational drug in another clinical trial within the last 4 weeks
- Subject is a regular user or past abuser of any illicit drug (including alcohol)
- Subject drinks excessive amounts of caffeinated beverages
- Subject has a history of cancer
- Subject has a history of prostate or testicular surgery
Trial design
Primary purpose
Treatment
Allocation
Randomized
Interventional model
Parallel Assignment
Masking
Double Blind
68 participants in 3 patient groups, including a placebo group
1
Experimental group
Description:
MK0773 + placebo injection
Treatment:
Drug: Comparator: placebo injection
Drug: MK0773
2
Active Comparator group
Description:
placebo to MK0773 + testosterone injection
Treatment:
Drug: Comparator: placebo oral tablet
Drug: Comparator: testosterone enanthate
3
Placebo Comparator group
Description:
placebo to MK0773 + placebo injection
Treatment:
Drug: Comparator: placebo oral tablet
Drug: Comparator: placebo injection
Trial contacts and locations
0
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal
© Copyright 2026 Veeva Systems